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In part, the reduction of general mortality could be due to the application of more sensible diagnostic criteria for acute myocardial infarction, most of all to cardiac troponin I, with consequent admission to CCU also for patients with a better prognosis.Trying to eliminate any confounding data, we’ve verified the trend of mortality only in patients admitted for ST–elevation myocardial infarction, verifying an improvement in the mortality trend.

Mean age, gender, and cardiovascular risk factors except for smoking were similar in both groups.These patients received anticoagulant and antiplatelets therapy in several combinations: UH plus A (430 pts), UH plus A&C (145 pts), E plus A (85 pts), E plus A&C (89 pts), UA followed by E plus A (45 pts) and UH followed by E plus A&C (68 pts).Results: The in-hospital mortality were high in UH plus A (13.25%), E plus A (12.94%) and UA followed by E plus A groups (8.88%) compared with UH plus A&C (6.20%) and E plus A&C (5.61%) groups.Methods: We analyzed consecutive patients presenting with STEMI within 12 hours after the onset of symptom and who were treated with primary percutaneous coronary intervention (PCI) from January 2008 through December 2009.In January 2009, a new parallel activation protocol from the first contact physician at the ED was introduced.

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320 (235–480) in Group B p Background: In the developing countries with few PCI-capable centers the use of the “full package” armamentarium (Unfractionated heparin – UH for 48–96 hours followed by Enoxaparin – E combined with dual antiplatelet therapy) can be a solution for the rise of the succesfull thrombolysis in diabetes patients (pts) with ST-elevation myocardial infarction (STEMI).

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